Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. Niacin is also present in many multiple vitamins and nutritional supplements.
Lovastatin is in a group of drugs called HMG CoA reductase inhibitors, or “statins.” Lovastatin reduces levels of “bad” cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of “good” cholesterol (high-density lipoprotein, or HDL).
The combination of lovastatin and niacin is used to lower cholesterol and triglycerides (types of fat) in the blood.
Advicor may also be used for other purposes not listed in this medication guide.
Most important: You should not take this medication if you are allergic to niacin (Niaspan, Niacor, and others) or lovastatin (Altoprev, Mevacor), if you are pregnant or breast-feeding, or if you have liver disease, severe bleeding, or a stomach ulcer. Stop taking this medication and tell your doctor right away if you become pregnant.
Before taking Advicor, tell your doctor if you have ever had liver or kidney disease, heart disease, diabetes, gout, or a thyroid disorder, if you have recently had a heart attack, or if you drink more than 2 alcoholic beverages daily.
In rare cases, Advicor can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.
There are many other drugs that can increase your risk of serious medical problems if you take them together with Advicor. Tell your doctor about all medications you use. Keep a list of all your medicines and show it to any healthcare provider who treats you.